Multiple HIV-1/M + HIV-1/O dual infections and new HIV-1/MO inter-group recombinant forms detected in Cameroon
نویسندگان
چکیده
منابع مشابه
Near full-length HIV type 1M genomic sequences from Cameroon
BACKGROUND Cameroon is the country in which HIV-1 group M (HIV-1M) likely originated and is today a major hotspot of HIV-1M genetic diversity. It remains unclear, however, whether the highly divergent HIV-1M lineages found in this country arose during the earliest phases of the global HIV-1M epidemic, or whether they arose more recently as a result of recombination events between globally circu...
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The high degree of human immunodeficiency virus type 1 (HIV-1) diversity in the Cameroonian population indicates a relatively old epidemic in this country. However, studies of pygmy 'hunter-gatherers' show only rare HIV-1 infection, mainly after contact with Bantus rather than from contact with non-human primates.
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The genetic diversity of group M HIV-1 is highest in west central Africa. Blood samples from four locations in Cameroon were collected to determine the molecular epidemiology of HIV-1. The C2-V5 region of envelope was sequenced from 39 of the 40 samples collected, and 7 samples were sequenced across the genome. All strains belonged to group M of HIV-1. The circulating recombinant form CRF02 AG ...
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ژورنال
عنوان ژورنال: Retrovirology
سال: 2017
ISSN: 1742-4690
DOI: 10.1186/s12977-016-0324-3